Information on this site is for research purposes only.

Close Icon

Category Archives: Cancer

Nitroxides as antioxidants – possibilities of their application in chemoprevention and radioprotection. [Article in Polish]

Postepy Hig Med Dosw (Online). 2011 Feb 2;65:46-54. [Article in Polish] Tabaczar S¹, Talar M, Gwoździński K. Abstract Nitroxides as stabile organic radicals were used initially as spin labels in spectroscopy of electron paramagnetic resonance (EPR) with respect to parameters such as pH of an intercellular environment, oxygenation of cells and tissues, fluidity of biological membranes, […]

Take a Tour 

Possible protective effect by SOD on UV damage in xeroderma pigmentosum (XP)

  J Invest Dermatol. 1989 Oct;93(4):506-10. Reduced superoxide dismutase activity in xeroderma pigmentosum fibroblasts. Nishigori C¹, Miyachi Y, Imamura S, Takebe H. ¹Department of Dermatology, Faculty of Medicine, Kyoto University, Japan. Abstract This study was performed in order to assess the possible protective effect of superoxide dismutase (SOD) on ultraviolet (UV) damage in xeroderma pigmentosum […]

Take a Tour 
Post Image

New Treatment Method to Help Women Suffering From Fibrocystic Disease

FOR IMMEDIATE RELEASE August 19, 2014 Fibrocystic disease may affect up to 50 percent of all women (INDIANAPOLIS, Ind.) –A new patent has been issued for a method that uses the SOD-mimetic agent TEMPOL to treat fibrocystic disease of the breast (FD). Approximately 20 percent of women suffering from FD, which is more commonly known […]

Take a Tour 
Post Image

Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor.

Hum Mol Genet. 2005 Jun 15;14(12):1699-708. Epub 2005 May 11. Erker L¹, Schubert R, Yakushiji H, Barlow C, Larson D, Mitchell JB, Wynshaw-Boris A. ¹Department of Pediatrics, UCSD School of Medicine, La Jolla, CA Abstract We previously demonstrated that the nitroxide antioxidant tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl) increased latency to tumorigenesis and doubled (100%) the lifespan of Atm-deficient […]

Take a Tour 
Post Image

Tempol Inhibits Pancreatic Cancer Cell Growth

Free Radical Biology and Medicine, Volume 49, Supplement, 2010, Pages S58 Du J¹, Olney K¹, Schrock H¹, Moser J¹, Wagner B¹, Sibenaller Z¹, Buettner G¹, Cullen J¹ ¹Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa ABSTRACT NOT AVAILABLE ONLINE – See full ARTICLE

Take a Tour 
Visit Us On TwitterVisit Us On FacebookVisit Us On Google PlusVisit Us On YoutubeCheck Our Feed