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Tag Archives: BRCA

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Tempol disrupts CtBP1 binding to Brca1

Oncogene. 2010 Dec 16;29(50):6603-8. Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1 Deng Y1, Liu J, Han G, Lu SL, Wang SY, Malkoski S, Tan AC, Deng C, Wang XJ, Zhang Q. 1Department of Dermatology, University of Colorado, Denver, Aurora, CO 80045, USA. Abstract C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor and metabolic […]

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