- 12, 29, 2014
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- By Admin
- Angiogenisis, Antioxidant, Cancer, Immune, Inflammation, Oxidative Stress
Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor.
Hum Mol Genet. 2005 Jun 15;14(12):1699-708. Epub 2005 May 11. Erker L¹, Schubert R, Yakushiji H, Barlow C, Larson D, Mitchell JB, Wynshaw-Boris A. ¹Department of Pediatrics, UCSD School of Medicine, La Jolla, CA Abstract We previously demonstrated that the nitroxide antioxidant tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl) increased latency to tumorigenesis and doubled (100%) the lifespan of Atm-deficient […]
Take a Tour- 12, 28, 2014
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- Antioxidant, Diabetes, Metabolic Syndrome, Oxidative Stress
Tempol reduces oxidative stress, improves insulin sensitivity.
Diabetes. 2005 Jul;54(7):2219-26. Banday AA¹, Marwaha A, Tallam LS, Lokhandwala MF. ¹Heart and Kidney Institute, University of Houston, Houston, Texas Abstract Oxidative stress plays a pathogenic role in hypertension, particularly the one associated with diabetes and obesity. Here, we test the hypothesis that renal dopamine D1 receptor dysfunction in obese Zucker rats is caused by […]
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