Investigation of antioxidant enzymes in children with autistic disorder.
Prostaglandins Leukot Essent Fatty Acids. 2002 Nov;67(5):341-3. Investigation of antioxidant enzymes in children with autistic disorder. Yorbik O1, Sayal A, Akay C, Akbiyik DI, Sohmen T. 1GATA Child and Adolescent Psychiatry Department, Etlik, Ankara, Turkey. Abstract Impaired antioxidant mechanisms are unable to inactivate free radicals that may induce a number of pathophysiological processes and result […]
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Oxidative stress in autism.
Pathophysiology. 2006 Aug;13(3):171-81. Oxidative stress in autism. Chauhan A1, Chauhan V. 1NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA. Abstract Autism is a severe developmental disorder with poorly understood etiology. Oxidative stress in autism has been studied at the membrane level and also by measuring products […]
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Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation.
Biol Trace Elem Res. 2011 Oct;143(1):58-65. Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation. Meguid NA1, Dardir AA, Abdel-Raouf ER, Hashish A. 1Department of Research on Children with Special Needs, National Research Center, Tahrir St, Cairo, Egypt. Abstract Autism is a neurodevelopmental disorder of childhood with poorly understood etiology and […]
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The mitochondrion: a perpetrator of acquired hearing loss.
Hear Res. 2013 Sep;303:12-9. The mitochondrion: a perpetrator of acquired hearing loss. Böttger EC1, Schacht J. 1Institut für Medizinische Mikrobiologie, Universität Zürich, Zürich, Switzerland. Abstract Age, drugs, and noise are major causes of acquired hearing loss. The involvement of reactive oxygen species (ROS) in hair cell death has long been discussed, but there is considerably […]
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Tempol, NAC and pioglitazone all restored cerebrovascular reactivity in aged Alzheimer’s disease transgenic mice.
J Neurosci. 2008 Sep 10;28(37):9287-96. Complete rescue of cerebrovascular function in aged Alzheimer’s disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. Nicolakakis N1, Aboulkassim T, Ongali B, Lecrux C, Fernandes P, Rosa-Neto P, Tong XK, Hamel E. 1Laboratory of Cerebrovascular Research, Montréal Neurological Institute, McGill University, Montréal, Québec, Canada. Abstract […]
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SOD2 and GSH are critical for the cellular antioxidant defense in neurodegenerative diseases and acute brain disorders.
Neurochem Int. 2015 Jan 6. Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders. Ruszkiewicz J1, Albrecht J2. 1Department of Neurotoxicology, Mossakowski Medical Research Centre, Polish Academy of Sciences, 02-106 Warsaw, Poland. 2Department of Neurotoxicology, Mossakowski Medical Research Centre, Polish Academy of Sciences, 02-106 Warsaw, Poland. Abstract Oxidative and nitrosative stress […]
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Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme.
J Biol Chem. 2014 Oct 31;289(44):30690-701. Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme. Coelho FR1, Iqbal A1, Linares E1, Silva DF1, Lima FS1, Cuccovia IM1, Augusto O2. 1From the Departamento de Bioquímica, Instituto de Química, Universidade de São […]
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Antioxidant defense capacity in scleroderma patients.
Clin Chem Lab Med. 2008;46(6):836-41. Antioxidant defense capacity in scleroderma patients. Sfrent-Cornateanu R1, Mihai C, Stoian I, Lixandru D, Bara C, Moldoveanu E. 1Department of Physiopathology and Immunology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania. Abstract BACKGROUND: Oxidative stress is associated with scleroderma (systemic sclerosis) and is supposed to favor disease progression by […]
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Intrathecal orgotein.
Int J Clin Pharmacol Res. 1985;5(1):59-62. Intrathecal orgotein. Lund-Olesen K. Abstract During the period 1971-78, 133 intrathecal injections of orgotein or superoxide dismutase have been given, mostly to patients with multiple sclerosis. Evaluation of the effect was deficient but the impression was that of improvement and 45% of the 58 patients with multiple sclerosis requested […]
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Novel autoantibody to Cu/Zn superoxide dismutase in patients with localized scleroderma.
J Invest Dermatol. 2004 Mar;122(3):594-601. Novel autoantibody to Cu/Zn superoxide dismutase in patients with localized scleroderma. Nagai M1, Hasegawa M, Takehara K, Sato S. 1Department of Dermatology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. Abstract Abnormal production of reactive oxygen species (ROS) induces tissue damage and superoxide dismutase (SOD) that converts superoxide radicals […]
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