Tempol, losartan and EB1089 provided protection against DNA damaging effects of glucose and HIV.
Cell Signal. 2015 Mar;27(3):460-9. Hyperglycemia enhances kidney cell injury in HIVAN through down-regulation of vitamin D receptors. Rai P1, Singh T1, Lederman R1, Chawla A1, Kumar D1, Cheng K1, Valecha G1, Mathieson PW1, Saleem MA1, Malhotra A1, Singhal PC2. 1Department of Medicine, Feinstein Institute for Medical Research, North Shore LIJ Medical School, NY, USA; Department […]Take a Tour
HIV Tat protein was prevented by antioxidant Tempol.
J Mol Cell Cardiol. 2011 Nov;51(5):876-80. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs. Bai YL1, Liu HB, Sun B, Zhang Y, Li Q, Hu CW, Zhu JX, Gong DM, Teng X, Zhang Q, Yang BF, Dong DL. 1Department of Pharmacology the State-Province Key Laboratories of Biomedicine-Pharmaceutics of […]Take a Tour
WR-1065 and Tempol protected MOLT-3 cells against specific types of AZT-induced DNA damage.
Environ Mol Mutagen. 2014 Aug;55(7):566-72. Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and Tempol. Olivero OA1, Ongele MO, Braun HM, Marrogi A, Divi K, Mitchell JB, Poirier MC. 1Carcinogen-DNA Interactions Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Abstract The cytokinesis-block […]Take a Tour