Fluoroquinolone antibiotics quenched by Tempol
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Dec 10;133:887-91. Fluorescence quenching of fluoroquinolone antibiotics by 4-hydroxy-TEMPO [Tempol} in aqueous solution. Żamojć K1, Wiczk W2, Zaborowski B2, Makowski M2, Pranczk J2, Jacewicz D2, Chmurzyński L2. 1University of Gdansk, Faculty of Chemistry, Wita Stwosza 63, 80-308 Gdansk, Poland. Electronic 2University of Gdansk, Faculty of Chemistry, Wita Stwosza […]
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SOD2 gene polymorphisms in psoriatic arthritis
Dis Markers. 2003-2004;19(6):263-5. Manganese superoxide dismutase gene polymorphisms in psoriatic arthritis. Yen JH1, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW 1Division of Rheumatology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan. jehsye@kmu.edu.tw Abstract The purpose of the present study is to investigate the role of manganese superoxide dismutase (MnSOD) gene polymorphisms […]
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Tempol for SOD and catalase deficiency in psoriasis
Indian J Clin Biochem. 2010 Oct;25(4):388-92. Role of oxidative stress in various stages of psoriasis. Kadam DP1, Suryakar AN, Ankush RD, Kadam CY, Deshpande KH. 1Department of Biochemistry, Dr. V. M. Govt. Medical College, Solapur, Maharashtra India. Abstract Psoriasis is a chronic inflammatory, proliferative skin disease characterized by pathological skin lesions due to various exogenous […]
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Tempol protects against UV cancer-causing mutations that occur hours after sun exposure.
Science 20 February 2015: Vol. 347 no. 6224 p. 824 Biomolecules The dark side of sunlight and melanoma John-Stephen Taylor Department of Chemistry, Washington University, St. Louis, MO 63130, USA. Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure. Summary Skin cancer is the […]
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Antioxidant defense capacity in scleroderma patients.
Clin Chem Lab Med. 2008;46(6):836-41. Antioxidant defense capacity in scleroderma patients. Sfrent-Cornateanu R1, Mihai C, Stoian I, Lixandru D, Bara C, Moldoveanu E. 1Department of Physiopathology and Immunology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania. Abstract BACKGROUND: Oxidative stress is associated with scleroderma (systemic sclerosis) and is supposed to favor disease progression by […]
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The conservative treatment of Peyronie’s disease with orgotein
Khirurgiia (Sofiia). 1989;42(6):57-9. The conservative treatment of Peyronie’s disease with orgotein. [Article in Bulgarian] Ianev V, Tsvetkov D. Abstract Results are analyzed of treatment of patients with induratio penis plastica by local application of orgotein. Fifteen patients with clinically manifest disease were the subject of this study; 4-8 mg Orgotein bulk was applied once a […]
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Orgotein in the treatment of plastic induration of the penis (Peyronie’s disease).
Int Urol Nephrol. 1993;25(2):169-72. Orgotein in the treatment of plastic induration of the penis (Peyronie’s disease). Primus G1. 1Department of Urology, LKH, Graz, Austria. Abstract Eighteen patients with Peyronie’s disease have been treated with the anti-inflammatory metalloprotein Orgotein, which exhibits a pronounced superoxide dismutase activity. Only patients with severe symptoms were selected. The drug was […]
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Novel autoantibody to Cu/Zn superoxide dismutase in patients with localized scleroderma.
J Invest Dermatol. 2004 Mar;122(3):594-601. Novel autoantibody to Cu/Zn superoxide dismutase in patients with localized scleroderma. Nagai M1, Hasegawa M, Takehara K, Sato S. 1Department of Dermatology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. Abstract Abnormal production of reactive oxygen species (ROS) induces tissue damage and superoxide dismutase (SOD) that converts superoxide radicals […]
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Topical application of superoxide dismutase cream.
Drugs Exp Clin Res. 1991;17(2):127-31. Topical application of superoxide dismutase cream. Mizushima Y1, Hoshi K, Yanagawa A, Takano K. 1Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan. Abstract A superoxide dismutase (SOD) cream containing 0.6 mg/ml of bovine SOD was prepared. It was applied locally onto the skin and mucosal lesions […]
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Chromosome instability in human and murine autoimmune disease: anticlastogenic effect of superoxide dismutase.
Acta Physiol Scand Suppl. 1980;492:59-65. Chromosome instability in human and murine autoimmune disease: anticlastogenic effect of superoxide dismutase. Emerit I, Michelson AM. Abstract Increased chromosome breakage is observed in lymphocyte cultures from patients with so-called autoimmune diseases also in the animal model, the NZB mouse. A clastogenic agent was detected in the serum of […]
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