Endothelial dysfunction caused by Agent Orange induced ROS was restored by Tempol
Cardiovasc Toxicol. 2008 Dec;8(4):181-93. Hypertension, cardiac hypertrophy, and impaired vascular relaxation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are associated with increased superoxide. Kopf PG1, Huwe JK, Walker MK. 1College of Pharmacy, University of New Mexico Health Sciences Center, MSC09 5360, 2502 Marble NE, Albuquerque, NM 87131, USA. Abstract The mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increases the incidence of […]
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Benefits of losartan and tempol in renal inflammation by hypernatremia.
Free Radic Res. 2015 Apr;49(4):383-96. Role of angiotensin II and oxidative stress in renal inflammation by hypernatremia: Benefits of atrial natriuretic peptide, losartan, and tempol. Della Penna SL1, Rosón MI, Toblli JE, Fernández BE. 1Department of Pathophysiology, School of Pharmacy and Biochemistry, University of Buenos Aires , Argentina. Abstract The body regulates plasma sodium levels […]
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Tempol ameliorates ROS and apnea-induced hypertension.
Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2971-6. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. Troncoso Brindeiro CM1, da Silva AQ, Allahdadi KJ, Youngblood V, Kanagy NL. 1Department of Cell Biology and Physiology, University of New Mexico, Albuquerque, NM 87131, USA. Abstract In clinical studies, sleep apnea is associated with hypertension, oxidative […]
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The role of redox balance in vascular dysfunction and chronic obstructive pulmonary disease.
Hypertension. 2014 Mar;63(3):459-67. Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance. Ives SJ1, Harris RA, Witman MA, Fjeldstad AS, Garten RS, McDaniel J, Wray DW, Richardson RS. 1VA Medical Center Bldg 2, Rm 1D25, 500 Foothill Dr, Salt Lake City, UT 84148. Abstract Chronic obstructive pulmonary disease (COPD) is characterized by […]
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Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD).
Pharmacol Res. 2014 Mar;81:91-102. Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD). Impellizzeri D1, Esposito E1, Attley J2, Cuzzocrea S3. 1Department of Biological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres, Messina 31-98166, Italy. 2Prismic Pharmaceuticals, Scottsdale, AZ, USA. 3Department of Biological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno […]
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Transcriptional Regulation of Renal Dopamine D1 Receptor Function During Oxidative Stress.
Hypertension. 2015 Mar 2. Transcriptional Regulation of Renal Dopamine D1 Receptor Function During Oxidative Stress. Banday AA1, Lokhandwala MF2. 1From the Heart and Kidney Institute, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, TX. 2From the Heart and Kidney Institute, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of […]
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Antihypertensive effect of mitochondria-targeted proxyl nitroxides.
Redox Biol. 2015;4:355-62. Antihypertensive effect of mitochondria-targeted proxyl nitroxides. Dikalova AE1, Kirilyuk IA2, Dikalov SI3. 1Vanderbilt University Medical Center, 2200 Pierce Avenue, Nashville, TN 37232, USA. 2Novosibirsk Institute of Organic Chemistry, Lavrentieva 9, Novosibirsk 630090, Russia; Novosibirsk State University, Pirogova 2, Novosibirsk 630090, Russia. 3Vanderbilt University Medical Center, 2200 Pierce Avenue, Nashville, TN 37232, USA. […]
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Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction.
J Gerontol A Biol Sci Med Sci. 2015 Mar 3. Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction. Bhayadia R1, Schmidt BM2, Melk A1, Hömme M1. 1Department of Pediatric Nephrology, Hepatology and Metabolic Diseases, Children’s Hospital, Hannover Medical School, Hannover D-30625, Germany. REBIRTH Excellence Cluster, Hannover Medical School, Hannover D-30625, Germany. 2Department of Nephrology, Hannover Medical School, […]
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Tempol protects blood proteins and lipids against peroxynitrite-mediated oxidative damage.
Exp Biol Med (Maywood). 2015 Jan;240(1):109-12. Tempol protects blood proteins and lipids against peroxynitrite-mediated oxidative damage. Mustafa AG1, Bani-Ahmad MA2, Jaradat AQ2, Allouh MZ3. 1Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan. 2Department of Medical Laboratories, Faculty of Allied Medical Sciences, Jordan University of Science and Technology, Irbid […]
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Therapeutic and Clinical Applications of Nitroxide Compounds
Antioxid Redox Signal. 2007 Oct;9(10):1731-43. Forum Review: Therapeutic and clinical applications of nitroxide compounds. Soule BP¹, Hyodo F, Matsumoto K, Simone NL, Cook JA, Krishna MC, Mitchell JB. ¹ Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland Abstract Nitroxide compounds have been used for many years as biophysical tools, but only […]
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