Investigation of antioxidant enzymes in children with autistic disorder.
Prostaglandins Leukot Essent Fatty Acids. 2002 Nov;67(5):341-3. Investigation of antioxidant enzymes in children with autistic disorder. Yorbik O1, Sayal A, Akay C, Akbiyik DI, Sohmen T. 1GATA Child and Adolescent Psychiatry Department, Etlik, Ankara, Turkey. Abstract Impaired antioxidant mechanisms are unable to inactivate free radicals that may induce a number of pathophysiological processes and result […]
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Oxidative stress in autism.
Pathophysiology. 2006 Aug;13(3):171-81. Oxidative stress in autism. Chauhan A1, Chauhan V. 1NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA. Abstract Autism is a severe developmental disorder with poorly understood etiology. Oxidative stress in autism has been studied at the membrane level and also by measuring products […]
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Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation.
Biol Trace Elem Res. 2011 Oct;143(1):58-65. Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation. Meguid NA1, Dardir AA, Abdel-Raouf ER, Hashish A. 1Department of Research on Children with Special Needs, National Research Center, Tahrir St, Cairo, Egypt. Abstract Autism is a neurodevelopmental disorder of childhood with poorly understood etiology and […]
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Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening.
J Biol Chem. 2003 Feb 28;278(9):6824-30. Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening. Serra V1, von Zglinicki T, Lorenz M, Saretzki G. 1Institute of Pathology and Research Laboratory Cardiology, Charité Hospital, D-10098 Berlin, Germany. Abstract There is good evidence that telomere shortening acts as a biological clock in […]
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WR-1065 and Tempol protected MOLT-3 cells against specific types of AZT-induced DNA damage.
Environ Mol Mutagen. 2014 Aug;55(7):566-72. Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and Tempol. Olivero OA1, Ongele MO, Braun HM, Marrogi A, Divi K, Mitchell JB, Poirier MC. 1Carcinogen-DNA Interactions Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Abstract The cytokinesis-block […]
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The mitochondrion: a perpetrator of acquired hearing loss.
Hear Res. 2013 Sep;303:12-9. The mitochondrion: a perpetrator of acquired hearing loss. Böttger EC1, Schacht J. 1Institut für Medizinische Mikrobiologie, Universität Zürich, Zürich, Switzerland. Abstract Age, drugs, and noise are major causes of acquired hearing loss. The involvement of reactive oxygen species (ROS) in hair cell death has long been discussed, but there is considerably […]
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Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant Tempol.
Cancer Lett. 2014 Oct 28;353(2):248-57 Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant Tempol. Georgakilas AG1, Redon CE2, Ferguson NF3, Kryston TB3, Parekh P2, Dickey JS4, Nakamura AJ5, Mitchell JB6, Bonner WM2, Martin OA7. 1Department of Biology, Thomas Harriot College of Arts and Sciences, East Carolina University, Greenville, […]
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A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss.
Mech Ageing Dev. 2013 Jul-Aug;134(7-8):298-306. A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss. Nolan LS1, Cadge BA, Gomez-Dorado M, Dawson SJ. 1Centre for Auditory Research, Ear Institute, University College London, 332 Gray’s Inn Road, London WC1X 8EE, UK. Abstract Genetic variation in superoxide dismutase 2 (SOD2) is […]
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The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea.
Hear Res. 2006 Apr;214(1-2):1-6. The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea. Murashita H1, Tabuchi K, Hoshino T, Tsuji S, Hara A. 1Department of Otolaryngology, Tsukuba University Hospital, Tsukuba, Japan. Abstract Oxygen free radicals have been implicated in the pathogenesis of acoustic injury of the cochlea. […]
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The role of redox balance in vascular dysfunction and chronic obstructive pulmonary disease.
Hypertension. 2014 Mar;63(3):459-67. Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance. Ives SJ1, Harris RA, Witman MA, Fjeldstad AS, Garten RS, McDaniel J, Wray DW, Richardson RS. 1VA Medical Center Bldg 2, Rm 1D25, 500 Foothill Dr, Salt Lake City, UT 84148. Abstract Chronic obstructive pulmonary disease (COPD) is characterized by […]
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