Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction.
J Gerontol A Biol Sci Med Sci. 2015 Mar 3. Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction. Bhayadia R1, Schmidt BM2, Melk A1, Hömme M1. 1Department of Pediatric Nephrology, Hepatology and Metabolic Diseases, Children’s Hospital, Hannover Medical School, Hannover D-30625, Germany. REBIRTH Excellence Cluster, Hannover Medical School, Hannover D-30625, Germany. 2Department of Nephrology, Hannover Medical School, […]
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Tempol protects blood proteins and lipids against peroxynitrite-mediated oxidative damage.
Exp Biol Med (Maywood). 2015 Jan;240(1):109-12. Tempol protects blood proteins and lipids against peroxynitrite-mediated oxidative damage. Mustafa AG1, Bani-Ahmad MA2, Jaradat AQ2, Allouh MZ3. 1Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan. 2Department of Medical Laboratories, Faculty of Allied Medical Sciences, Jordan University of Science and Technology, Irbid […]
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Tempol protects human lymphocytes from genotoxicity induced by cisplatin.
Int J Clin Exp Med. 2014 Apr 15;7(4):982-8 Tempol protects human lymphocytes from genotoxicity induced by cisplatin. Khabour OF1, Alzoubi KH2, Mfady DS1, Alasseiri M1, Hasheesh TF1. 1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology Irbid, Jordan. 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of […]
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Antioxidant defense capacity in scleroderma patients.
Clin Chem Lab Med. 2008;46(6):836-41. Antioxidant defense capacity in scleroderma patients. Sfrent-Cornateanu R1, Mihai C, Stoian I, Lixandru D, Bara C, Moldoveanu E. 1Department of Physiopathology and Immunology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania. Abstract BACKGROUND: Oxidative stress is associated with scleroderma (systemic sclerosis) and is supposed to favor disease progression by […]
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The conservative treatment of Peyronie’s disease with orgotein
Khirurgiia (Sofiia). 1989;42(6):57-9. The conservative treatment of Peyronie’s disease with orgotein. [Article in Bulgarian] Ianev V, Tsvetkov D. Abstract Results are analyzed of treatment of patients with induratio penis plastica by local application of orgotein. Fifteen patients with clinically manifest disease were the subject of this study; 4-8 mg Orgotein bulk was applied once a […]
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Orgotein in the treatment of plastic induration of the penis (Peyronie’s disease).
Int Urol Nephrol. 1993;25(2):169-72. Orgotein in the treatment of plastic induration of the penis (Peyronie’s disease). Primus G1. 1Department of Urology, LKH, Graz, Austria. Abstract Eighteen patients with Peyronie’s disease have been treated with the anti-inflammatory metalloprotein Orgotein, which exhibits a pronounced superoxide dismutase activity. Only patients with severe symptoms were selected. The drug was […]
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Pre-arrest administration of the cell-permeable free radical scavenger tempol reduces warm ischemic damage of lung function in non-heart-beating donors.
J Heart Lung Transplant. 2008 Aug;27(8):890-7. doi: 10.1016/j.healun.2008.05.019. Epub 2008 Jul 3. Pre-arrest administration of the cell-permeable free radical scavenger tempol reduces warm ischemic damage of lung function in non-heart-beating donors. Hodyc D1, Hnilickova O, Hampl V, Herget J. 1Department of Physiology, Second Medical School, Charles University of Prague, Prague, Czech Republic. BACKGROUND: Lungs retrieved […]
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TEMPOL-H for Fibrocystic Breast Disease– Case Report.
SFRBM (Society For Free Radical Biology and Medicine) Meeting, Nov. 20-24, 2013, San Antonio, TX Peter Proctor, Donna RollingProctor ABSTRACT Variably presenting with painful cysts and mastodynia, fibrocystic disease of breast (FD) affects 30-40% of women. FD complicates breast cancer diagnosis by requiring work-up of lumps to rule-out malignancy and by obscuring malignant lesions. Although […]
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Therapeutic and Clinical Applications of Nitroxide Compounds
Antioxid Redox Signal. 2007 Oct;9(10):1731-43. Forum Review: Therapeutic and clinical applications of nitroxide compounds. Soule BP¹, Hyodo F, Matsumoto K, Simone NL, Cook JA, Krishna MC, Mitchell JB. ¹ Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland Abstract Nitroxide compounds have been used for many years as biophysical tools, but only […]
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Nitroxides as antioxidants – possibilities of their application in chemoprevention and radioprotection. [Article in Polish]
Postepy Hig Med Dosw (Online). 2011 Feb 2;65:46-54. [Article in Polish] Tabaczar S¹, Talar M, Gwoździński K. Abstract Nitroxides as stabile organic radicals were used initially as spin labels in spectroscopy of electron paramagnetic resonance (EPR) with respect to parameters such as pH of an intercellular environment, oxygenation of cells and tissues, fluidity of biological membranes, […]
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