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Tag Archives: Mutagens

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WR-1065 and Tempol protected MOLT-3 cells against specific types of AZT-induced DNA damage.

Environ Mol Mutagen. 2014 Aug;55(7):566-72. Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and Tempol. Olivero OA1, Ongele MO, Braun HM, Marrogi A, Divi K, Mitchell JB, Poirier MC. 1Carcinogen-DNA Interactions Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Abstract The cytokinesis-block […]

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Chromosome instability in human and murine autoimmune disease: anticlastogenic effect of superoxide dismutase.

Acta Physiol Scand Suppl. 1980;492:59-65.  Chromosome instability in human and murine autoimmune disease: anticlastogenic effect of superoxide dismutase.  Emerit I, Michelson AM.   Abstract Increased chromosome breakage is observed in lymphocyte cultures from patients with so-called autoimmune diseases also in the animal model, the NZB mouse. A clastogenic agent was detected in the serum of […]

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